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Coptis teeta Wall., commonly known as Mishmi Tita, is a perennial herb native to the Eastern Himalayas and traditionally revered in the indigenous medicine of Arunachal Pradesh, India. It belongs to the Ranunculaceae family and is primarily valued for its yellow rhizomes, which are used extensively for treating digestive, hepatic, and infectious diseases. Due to its limited habitat and overharvesting, it is now considered endangered.
The rhizome of Coptis teeta is the most pharmacologically active part and is prepared as decoctions, powders, or tinctures in traditional medicine. Modern research confirms many of its folk uses, particularly its antibacterial, anti-inflammatory, and antioxidant actions.
Table of contents
Phytochemical Composition
Coptis teeta contains a rich profile of alkaloids and other therapeutic compounds:
- Berberine: A potent isoquinoline alkaloid with antimicrobial, anti-inflammatory, and blood glucose-lowering effects.
- Palmatine: Known for antibacterial and hepatoprotective properties.
- Coptisine and Epiberberine: Support digestive and cardiovascular health.
- Jatrorrhizine: Provides antioxidant and anti-inflammatory action.
5 Key Health Benefits of Coptis teeta
1. Antimicrobial and Antiviral Activity
Berberine and palmatine in Coptis teeta have demonstrated broad-spectrum activity against bacteria and viruses, including Staphylococcus aureus and Helicobacter pylori, supporting its traditional use in treating infections (Chelleng et al., 2024).
2. Anti-inflammatory Effects
Alkaloids from Coptis teeta reduce inflammatory markers such as TNF-α and IL-6, making it useful in managing inflammatory conditions like gastritis, arthritis, and metabolic syndrome (Bora et al., 2022).
3. Antioxidant Properties
The plant’s polyphenolic and alkaloid content scavenges free radicals, protecting cells from oxidative damage and contributing to chronic disease prevention (Bora et al., 2022).
4. Digestive and Hepatic Support
Traditionally used to relieve dysentery, diarrhea, indigestion, and liver dysfunction, berberine and jatrorrhizine in the plant improve bile flow and support detoxification (Chelleng et al., 2024).
5. Blood Sugar Regulation
Berberine has been extensively studied for its antidiabetic effects, including improving insulin sensitivity and lowering fasting blood glucose levels, supporting Coptis teeta’s role in managing metabolic disorders (Liu et al., 2021).
Traditional Medicinal Uses
Coptis teeta has been traditionally used to:
- Treat digestive issues like diarrhea, dyspepsia, and gastritis
- Manage liver disorders such as jaundice and hepatitis
- Reduce fever and symptoms of malaria
- Alleviate bacterial skin infections and eye conditions
Recommended Usage
- Decoction: 1–3 grams of dried rhizome simmered in water, taken 1–2 times daily.
- Powdered Rhizome: Can be taken in capsules or mixed into liquids.
- Tincture/Extract: Use standardized extracts per manufacturer or practitioner guidance.
Safety and Side Effects
- Pregnancy and Lactation: Avoid use due to lack of safety data.
- Drug Interactions: May enhance effects of antidiabetic or antihypertensive drugs.
- Toxicity: High doses of berberine may cause gastrointestinal upset or lower blood pressure; always follow professional advice.
Frequently Asked Questions (FAQs)
What is Coptis teeta used for?
Traditionally used to treat digestive and liver disorders, fevers, and infections.
Is Coptis teeta safe for long-term use?
Short-term traditional use is generally safe; consult a healthcare provider for long-term application.
Can Coptis teeta help manage blood sugar?
Yes, berberine in the herb supports blood sugar regulation.
Why is Coptis teeta considered endangered?
Due to its limited habitat, slow growth, and overharvesting, it is now a protected species requiring conservation.
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References:
Chelleng, N., et al. (2024). Coptis teeta Wall.: A comprehensive overview of its traditional uses, pharmacological properties, and conservation needs. Future Integrative Medicine, 3(1), 21–34. https://doi.org/10.14218/FIM.2023.00082
Bora, H., et al. (2022). Evaluation of phytochemicals, antioxidant, and antibacterial activities of Coptis teeta. International Journal of Pharmaceutical Sciences and Research, 13(4), 1835–1842. https://doi.org/10.13040/IJPSR.0975-8232.13(4).1835-42
Liu, W., et al. (2021). Berberine and its applications in metabolic disease management. RSC Advances, 11(50), 31465–31482. https://doi.org/10.1039/D1RA05090G
Berberine and palmatine in Coptis teeta have demonstrated broad-spectrum activity against bacteria and viruses, including Staphylococcus aureus and Helicobacter pylori, supporting its traditional use in treating infections.
Alkaloids from Coptis teeta reduce inflammatory markers such as TNF-α and IL-6, making it useful in managing inflammatory conditions like gastritis, arthritis, and metabolic syndrome.
The plant’s polyphenolic and alkaloid content scavenges free radicals, protecting cells from oxidative damage and contributing to chronic disease prevention.
Traditionally used to relieve dysentery, diarrhea, indigestion, and liver dysfunction, berberine and jatrorrhizine in the plant improve bile flow and support detoxification.
Berberine has been extensively studied for its antidiabetic effects, including improving insulin sensitivity and lowering fasting blood glucose levels, supporting Coptis teeta’s role in managing metabolic disorders.